Aims : to discuss 1) the various steps involved in confirming a diagnosis of severe asthma, 2) investigation of comorbidities and alternative diagnoses, 3) the role of a multidisciplinary team (nurses, physiotherapists and psychologists) and 4) a stratified approach to biologics. Each talk will present a clinical case scenario where severe asthma may be present, and describe the diagnostic and therapeutic approaches that should be adopted. With the aid of the case presentations, participants will understand the pathway that needs to be taken for the diagnosis and treatment of paediatric severe asthma.