Aims : Access educational materials here to update both paediatric and adult professionals involved in cystic fibrosis (CF) care on the recent advances in many important aspects of CF; to describe the latest knowledge about CF transmembrane conductance regulator (CFTR) dysfunction in CF and how this influences the different organs and leads to new treatments modalities; and to address the special needs caused by CF as an adult disease, namely, the transition of adolescents into adult care, fertility and end-of-life issues.