Do we really need PD1/PD-L1 status and next generation sequencing to treat lung cancer?
Aims : Today, immunooncology has almost completely revolutionised the treatment of various cancer types, especially lung cancer. Moreover, encouraging preliminary data are available for mesothelioma. These entities respond to PD-1 and PD-L1 inhibition. In addition, more and more targeted agents for lung cancer therapy are becoming available: these agents go beyond the tyrosine kinase blockade of mutated EGFR and rearranged ALK. Another marked advance is Next Generation Sequencing (NGS), which facilitates the detection of many dozens of mutations at the same time. However, the provocative question from the clinical standpoint remains: is detailed molecular testing essential for treating patients with these drugs?
Target audience :
Clinician, Pathologist, Public health official, Pulmonologist, Respiratory physician, Thoracic surgeon, Fellow, Immunologist, Junior member, Oncologist, Pharmaceutical industry representative, Researcher, Resident, Scientist, Student