Airway diseases
Interstitial lung diseases
Hot topics
(Re-)discovering the small airway epithelium in COVID-19, fibrosing lung diseases and pulmonary regeneration
Basic science
Aims : To summarize the clinical evidence for a pathogenic role of small airway cells in COVID-19 and fibrosing lung diseases; to explore the novel concept that small airways are central to the processes involved in regenerating and repairing a fibrosing lung. New developments regarding innovative in vitro models will allow us to exploit the regenerative and therapeutic potential of modulating small airway cells in lung fibrosis. AIMS: To highlight the contribution of small airway cells in COVID-19 and lung fibrosis from a clinical perspective; to understand the key role of small airway cells in lung regeneration and fibrosis; to demonstrate the regenerative potential of small airway cells and their likelihood as new therapeutic targets for pulmonary fibrosis; to explore novel models to study small airway cells and their regenerative capacities in pulmonary fibrosing diseases.
Target audience :
Clinical researcher, Medical Student, Pathologist, Scientist (basic, translational), Thoracic surgeon
14:30
Introduction
1
4598
14:35
The role of bronchial epithelial cells in COVID-19 infection and pathogenesis
S. Trump(Berlin, Germany)
COI
2
4599
14:45
Airway basal cell involvement in idiopathic pulmonary fibrosis
A. Prasse(Hannover, Germany)
COI
-
Description
3
4600
14:55
Uncovering the plasticity of lung epithelial cells by scRNA sequencing
H. Schiller(Munich, Germany)
COI
-
Description
4
4601
15:05
Modeling the regenerative potential of airway epithelial cells
P. Hiemstra(Leiden, Netherlands)
COI
-
Description
5
4602
15:15
Discussion and Q&A
6
4603
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