COVID-19
Basic science
Basic science
Aims : This session will explain the basic science behind the SARS CoV 2 virus, covering factors from the structure, viral entry, genomic epidemiology, immune response, and lung effects.
Key references:
1: McCallum M, Walls AC, Bowen JE, Corti D, Veesler D. Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation. Nat Struct Mol Biol. 2020 Aug 4. doi: 10.1038/s41594-020-0483-8.Epub ahead of print. PMID: 32753755.
2: Walls AC, Park YJ, Tortorici MA, Wall A, McGuire AT, Veesler D. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell. 2020 Apr 16;181(2):281-292.e6. doi: 10.1016/j.cell.2020.02.058. Epub 2020 Mar 9. PMID:32155444; PMCID: PMC7102599.
Target audience :
Adult pulmonologist/Clinician, Clinical researcher, General practitioner, Nurse, Paediatrician, Physiologist, Respiratory critical care physician, Respiratory physiotherapist, Scientist (basic, translational), Thoracic oncologist, Thoracic surgeon, Respiratory therapist, Physician in Pulmonary Training
Methods :
Cell and molecular biology
09:40
Introduction
1
COV3605
09:45
Virus biology (structure, viral entry and genomic epidemiology of virus)
M. Koopmans(Rotterdam, Netherlands)
COI
2
COV3607
10:00
Host response (immune response)
T. Hussell(Manchester (Greater Manchester), United Kingdom)
COI
3
COV3608
10:15
Host response (airway/lung effects)
G. Jenkins(London, United Kingdom)
COI
4
COV3609
10:30
Discussion and questions and answers
5
COV3610
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