Aims : to empower the participants to use the Human Lung Cell Atlas for their own translational or basic research. To achieve this, the hot topic symposium at ERS2022 will introduce the Human Lung Cell Atlas, provide examples of the use of the Atlas, and illustrate the value of the Atlas for basic and translational research into lung diseases. After this symposium, the participants will be able to find the Human Lung Cell Atlas, to access the Atlas for gene- or cell-type-oriented queries for their own research activities, to use the Atlas for harmonised cell-type annotation of their own datasets and to contrast their own data from lung disease samples to the universal healthy reference present in the Atlas.